Colistin Sulphate & Amoxycillin Trihydrate WSP
Per 1 gram powder contains:
Colistin Sulphate ……..…………2 000 000 IU.
Amoxycillin Trihydrate …..……200 mg.
The combination of amoxicillin and colistin. Amoxicillin is a semisynthetic broad-spectrum penicillin with a bactericidal action against both Gram-positive and Gram-negative bacteria. The range of effect includes Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase-negative Staphylococcus and Streptococcus, spp. The bactericidal action is due to inhibition of cell wall synthesis. Amoxicillin is mainly excreted in urine. A major part can also be excreted in bile. Colistin is an antibiotic from the group of polymyxins with a bactericidal action against Gram-negative bacteria like E. coli, Haemophilus and Salmonella. Since colistin is absorbed for a very small part after oral administration only gastrointestinal indications are relevant.
Gastrointestinal, respiratory and urinary tract infections caused by amoxicillin and colistin sensitive micro-organisms in calves, goats, poultry, sheep and swine. For example, Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp.
1. Hypersensitivity to amoxicillin and/or colistin.
2. Animals with seriously impaired renal function.
3. Concurrent administration of tetracyclines, chloramphenicol, macrolides and lincosamides.
4. Administration to animals with an active microbial digestion.
Hypersensitivity reactions, renal dysfunction, neurotoxicity and neuromuscular blockade.
For oral administration:
Calves, goats and sheep: Twice daily, 5 g per 100 kg body weight for 3 - 5 days.
Poultry and swine : 1 kg per 1000 - 2000 litres of drinking water for 3 - 5 days.
Note: for pre-ruminant calves, lambs and young animals only.
Please note: Before adding to the drinking water make solution of 1 kg per 20 liters of water under temperature of 40º C.
For meat: 8 days.
Keep out of reach of children.
Sachet of 100 g and jar of 500g or 1000 g.
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